Case contribution: Dr Radhiana Hassan
- A 59 years old came for screening mammogram
- Had mammogram done 3 years ago was normal
- No family history of breast cancer
- Bilateral fatty breasts (BIRADS A)
- An area of focal density with stromal distortion at lower inner quadrant of right breast (red circle)
- No suspicious clustered microcalcification
- No skin thickening or nipple retraction
- An ill-defined hypoechoic lesions at Rt5-6H
- The lesion shows significant posterior shadowing
- No ductal dilatation
- No abnormal axillary nodes
Progress of patient:
- Trucut biopsy done shows infiltrating ductal carcinoma.
- Right mastectomy and axillary clearance done
- DCIS component seen, no vascular invasion, no LNs involvement (20 LN removed), ER/PR +ve and HER2 +1
- Impression: Invasive carcinoma of nonspecific type Grade 1 (T1MoNx)
Diagnosis: Breast carcinoma: invasive nonspecific type
- Invasive carcinoma of no special type (NST) also known as invasive ductal carcinoma or ductal NOS and previously known as invasive ductal carcinoma, not otherwise specified (NOS)
- It is a group of breast cancers that do not have the “specific differentiating features”.
- It is the most common form of invasive breast cancer. It accounts for 55% of breast cancer incidence upon diagnosis.